It can be used for almost everything, except, perhaps the Ark of Sotek, which specifically references the numbers on the dice rolled. It's really good to apply to a d3 roll, since it affects the result. A d3 is effectively a die that reads "1, 1, 2, 2, 3, 3". The troglodon can benefit a lot from Curse of Fates, as it significantly increases the likelihood that it deals a wound.